Intoxicación por cafeína en un recien nacido prematuro Caffeine citrate is used as first-line therapy in neonates to treat or prevent apnea of prematurity. This is not the most recent version of this Review. Please comment on the current version. view the current version 20 Jan Si su bebé no tenía apnea ni bradicardia en UCIN o si la frecuencia o puede recibir medicamentos (teofilina o cafeína) para disminuir los episodios. Los bebés recién nacidos prematuros corren el riesgo de hernias, que.

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One limitation of this study is the lack of comparison in the number of apnea spells between both groups.

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Serum levels of caffeine in umbilical cord and apnea of prematurity. Long-term effects of caffeine therapy for apnea of prematurity.

To determine the influence of presence of caffeine in umbilical cord blood on apnea occurrence. Transplacentally acquired caffeine and the occurrence of apnea, bradycardia, and periodic breathing in preterm infants: Group 1 was formed by 87 newborns and group 2 by Pfematuro characteristics were analyzed using chi-square test, Fisher’s exact test, except for the birth weight variable Student’s t test and Apgar score Mann-Whitney test.

J Pediatr Rio J. Results Umbilical blood was collected in preterm neonates; 21 of them were subsequently excluded seven for presenting apnea once with no need for treatment, five for remaining in mechanical ventilation until the fourth day of life, three for PIVH degrees 3 and 4, one for exchange transfusion, five for methylxantine prior to extubationand three were lost two due to insufficient sampled quantity for caffeine dosage and one due to family request.


Diagnosis of apnea was performed through patient’s monitoring, and it was defined as interruption of breathing for 20 s or more, or interruption of shorter duration if followed by cyanosis, hypotension or bradyarrhythmia.

High-pressure liquid chromatography HPLC was the method used to determine caffeine, which has been employed in several studies on caffeine dosage. Fri 19 Jan – Premaguro was no association between occurrence of apnea spells and presence of caffeine in umbilical cord blood.

Newborns were followed for the first 4 days for occurrence of apnea spells. The study excluded neonates whose mothers received opioids or drugs that led to respiratory center depression, neonates who remained in mechanical ventilation during the first 4 days of life, with cerebral congenital malformations, perinatal asphyxia Apgar score under 7 at the 5th minute of lifePIVH degrees 3 and 4, major cardiac malformations, exchange transfusion before the fourth day of life, neonates who presented one isolated apnea with no need for drug or ventilatory treatment, and those that ddel methylxantine prior to extubation.

Carlos Gomes, cj.

Cochrane Database Syst Rev. ABC of antenatal care. Some studies quantified maternal use of caffeine during pregnancy.

La apnea aonea sueno en el bebe prematuro. Logistic regression analysis showed that none of those variables was associated with presence of caffeine in umbilical cord blood. For the diagnosis of meningitis, those with abnormal cerebrospinal fluid and positive culture were considered. None of them showed significance Table 3. Silveira II ;Renato S.

Definicion Apnea significa interrupcion de la respiracion. According to the service routine, preterm neonates whose birth weight was above 1, g and presented any clinical problem including apnea were submitted to CUS.

Como citar este artigo. Assessing caffeine exposure in pregnant women. No conflicts of interest declared concerning the publication of this article.

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Introduction Treatment of apnea of prematurity includes pharmacological approach with caffeine, a powerful stimulant of the central nervous system that reduces occurrence of neonatal apnea, promotes consolidation of a regular pattern of breathing and increases alveolar ventilation.

Sintomas de apnea del sueno en los bebes. Simultaneous determination of caffeine and its primary demethylated metabolites in human plasma by high-performance liquid chromatography.

A simple liquid chromatographic method applied to determine caffeine in plasma and tissues. Before the collection and inclusion, a consent term was read to the parents or person in charge.

Apnea del prematuro

Apnea del Prematuro “Sugerimos que “apnea” se defina como un intervalo sin respiracion que el recien nacido no pueda tolerar sin bradicardia o Algunos bebes que siguen teniendo apnea seran dados de alta del hospital con un monitor de apnea casero, con o sin cafeina, Bebe prematuro Siga leyendo. For the diagnosis of early sepsis, the study considered patients that presented clinical conditions and positive blood culture. Determination of caffeine, theophylline and theobromine in serum and saliva using high performance liquid chromatography.

Diagnosis and management of bacterial infections in the neonate. The study population was constituted by neonates with mean gestational age of Neonates were divided into detectable and undetectable caffeine in umbilical cord blood.

Pediatr Clin North Am. A prospective cohort study with preterm newborns with birth weight lower than 2, g was undertaken.